Core Biotechnology Services
Publications
Rzasa P, Whelan S, Farahmand P, Cai H, Guterman I, Palacios-Gallego R, Undru SS, Sandford L, Green C, Andreadi C, Mintseva M, Parrott E, Jin H, Hey F, Giblett S, Sylvius NB, Allcock NS, Straatman-Iwanowska A, Feuda R, Tufarelli C, Brown K, Pritchard C, Rufini A.Commun Biol. 2023 Sep 21;6(1):962. doi: 10.1038/s42003-023-05331-x.PMID: 37735514
Moorhouse AJ, Scholze M, Sylvius N, Gillham C, Rake C, Peto J, Anderson R, Dubrova YE.Sci Rep. 2022 Jul 5;12(1):10830. doi: 10.1038/s41598-022-14999-w.PMID: 35790751
Yang B, Sylvius N, Luo J, Yang C, Da Z, Crotty C, Nicholson ML. 2021 Front Immunol. 2021 Jul 1;12:657860. doi: 10.3389/fimmu.2021.657860. eCollection. PMID: 34276651
Kaur D, Chachi L, Gomez E, Sylvius N, Brightling CE. 2021 Clin Transl Immunology. 2021 Jun 26;10(6):e1301. doi: 10.1002/cti2.1301. eCollection 2021.
PMID: 34194747
Aamir A, Kuht HJ, McLean RJ, Maconachie GDE, Sheth V, Dawar B, Purohit R, Sylvius N, Hisaund M, Zubcov-Iwantscheff A, Proudlock FA, Gottlob I, Thomas MG. Sci Rep. 2021 Feb 2;11(1):2826. doi: 10.1038/s41598-021-82368-0. PMID: 33531592 Free PMC article
Kaur D, Chachi L, Gomez E, Sylvius N, Singh SR, Ramsheh MY, Saunders R, Brightling CE. Allergy. 2020 Dec;75(12):3184-3194. doi: 10.1111/all.14436. Epub 2020 Jul 27. PMID: 32516479
Kuht HJ, Han J, Maconachie GDE, Park SE, Lee ST, McLean R, Sheth V, Hisaund M, Dawar B, Sylvius N, Mahmood U, Proudlock FA, Gottlob I, Lim HT, Thomas MG. Hum Mol Genet. 2020 Nov 4;29(18):2989-3002. doi: 10.1093/hmg/ddaa166.PMID: 32744312 Free PMC article
Jafer A, Sylvius N, Adewoye AB, Dubrova YE. Mutat Res. 2020 May-Dec;821:111723. doi: 10.1016/j.mrfmmm.2020.111723. Epub 2020 Oct 11. PMID: 33096319
Turnbull RE, Fairall L, Saleh A, Kelsall E, Morris KL, Ragan TJ, Savva CG, Chandru A, Millard CJ, Makarova OV, Smith CJ, Roseman AM, Fry AM, Cowley SM, Schwabe JWR. Nat Commun, 2020 Jun 26;11(1):3252. doi: 10.1038/s41467-020-17078-8
Ekpenyong-Akiba AE, Poblocka M, Althubiti M, Rada M, Jurk D, Germano S, Kocsis-Fodor G, Shi Y, Canales JJ, Macip S. Aging Cell. 2020 Jan;19(1):e13079. doi: 10.1111/acel.13079. Epub 2019 Nov 17.
Chen Y, Peubez C, Smith V, Xiong S, Kocsis-Fodor G, Kennedy B, Wagner S, Balotis C, Jayne S, Dyer MJS, Macip S. J Cell Mol Med. 2019 Jan;23(1):340-348. doi: 10.1111/jcmm.13935. Epub 2018 Oct 24.
Alhegaili AS, Ji Y, Sylvius N, Blades MJ, Karbaschi M, Tempest HG, Jones GDD, Cooke MS. Int J Mol Sci. 2019 Oct 15;20(20):5112. doi: 10.3390/ijms20205112. PMID: 31618917 Free PMC article
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Toghill BJ, Saratzis A, Freeman PJ, Sylvius N; UKAGS collaborators, Bown MJ.Clin Epigenetics. 2018 Mar 2;10:29. doi: 10.1186/s13148-018-0460-9. eCollection 2018.PMID: 29507647 Free PMC article
Mitigating the effects of reference sequence bias in single-multiplex massively parallel sequencing of the mitochondrial DNA control region
Huszar TI, Wetton JH, Jobling MA. Forensic Sci Int Genet. 2019 Jan 16;40:9-17
A phylogenetic framework facilitates Y-STR variant discovery and classification via massively parallel sequencing
Huszar TI, Jobling MA, Wetton JH. Forensic Sci Int Genet. 2018 Jul;35:97-106
SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells
Toghill BJ, Saratzis A, Freeman PJ, Sylvius N, UKAGS collaborators, Bown MJ. Clinical Epigenetics, 2018 Mar 2;10:29
Erhardt S, Pocivavsek A, Repici M, Liu XC, Imbeault S, Maddison DC, Thomas MAR, Smalley JL, Larsson MK, Muchowski PJ, Giorgini F, Schwarcz R. Biol Psychiatry. 2017 Nov 15;82(10):756-765
Wright A, Mahaut-Smith M, Symon F, Sylvius N, Ran S, Bafadhel M, Muessel M, Bradding P, Wardlaw A, Vial C. J Immunol. 2016 May 9. pii: 1501585. [Epub ahead of print]
Butt HZ, Sylvius N, Salem MK, Wild JB, Dattani N, Sayers RD, Bown MJ. Eur J Vasc Endovasc Surg. 2016 May 2. pii: S1078-5884(16)00173-8. doi: 10.1016/j.ejvs.2016.03.016. [Epub ahead of print]
Jonczyk MS, Escudero L, Sylvius N, Norman M, Henriques-Normark B, Andrew PW. Infect Immun. 2016 Mar 24;84(4):894-905. doi: 10.1128/IAI.01057-15. Print 2016 Apr.
Identification of microRNAs associated with abdominal aortic aneurysms and peripheral arterial disease
Stather PW, Sylvius N, Sidloff DA, Dattani N, Verissimo A, Wild JB, Butt HZ, Choke E, Sayers RD, Bown MJ. Br J Surg. 2015 Jun;102(7):755-66. doi: 10.1002/bjs.9802. Epub 2015 Apr 2
Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection
Jonczyk MS, Simon M, Kumar S, Fernandes VE, Sylvius N, Mallon AM, Denny P, Andrew PW. PLoS One. 2014 Mar 3;9(3):e89831. doi: 10.1371/journal.pone.0089831. eCollection 2014
Stather PW, Sylvius N, Wild JB, Choke E, Sayers RD, Bown MJ. Circ Cardiovasc Genet. 2013 Oct;6(5):490-7. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
P.W. Stathera, J.B. Wild, N. Sylvius, E. Choke, R.D. Sayers, M.J. Bown. Artery Research, Volume 7, Issue 1, March 2013, Pages 28–35. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
Wild JB, Stather PW, Sylvius N, Choke E, Sayers RD, Bown MJ. Eur J Vasc Endovasc Surg. 2012 Aug;44(2):127-32. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
A mechanistic basis for amplification differences between samples and between genome regions
Veal CD, Freeman PJ, Jacobs K, Lancaster O, Jamain S, Leboyer M, Albanes D, Vaghela RR, Gut I, Chanock SJ, Brookes AJ. BMC Genomics. 2012 Sep 5;13:455.
Bown MJ, Jones GT, Harrison SC, Wright BJ, Bumpstead S, Baas AF, Gretarsdottir S, Badger SA, et al. Am J Hum Genet. 2011 Nov 11;89(5):619-27. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
Sylvius N, Bonne G, Straatman k, Reddy T, Gant TW, Shackleton S. FASEB J. 2011 Nov;25(11):3966-78. (With the department of Biochemistry, Âé¶¹ÊÓÆµ)
Campesan S, Green EW, Breda C, Sathyasaikumar KV, Muchowski PJ, Schwarcz R, Kyriacou CP, Giorgini F. Curr Biol. 2011 Jun 7;21(11):961-6. (With the department of Genetics, Âé¶¹ÊÓÆµ)
Pathway analysis shows association between FGFBP1 and hypertension
Tomaszewski M, Charchar FJ, Nelson CP, Barnes T, Denniff M, Kaiser M, Debiec R, et al. J Am Soc Nephrol. 2011 May;22(5):947-55. (With the department of Cardiovascular Sciences)
Edmondson, AC, Braund PS, Stylianou IM, Khera AV, Nelson CP, Wolfe ML, Derohannessian SL. et al. Circ Cardiovasc Genet. 2011 Apr;4(2):145-55. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
Reinhard W, Kaess BM, Debiec R, Nelson CP, Stark K, Tobin MD, Macfarlane PW et al. Circ Cardiovasc Genet. 2011 Apr;4(2):134-8. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
Tauber E, Miller-Fleming L, Mason RP, Kwan W, Clapp J, Butler NJ, Outeiro TF, Muchowski PJ, Giorgini F. J Biol Chem. 2011 Jan 7;286(1):410-9. (With the department of Genetics, Âé¶¹ÊÓÆµ)
Kaess BM, Tomaszewski M, Braund PS, Stark K, Rafelt S, Fischer M, Hardwick R, et al. PLoS One. 2011 Jan 21;6(1):e14529. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, et al. Am J Hum Genet. 2011 Jan 7;88(1):6-18. (With the department of Population Health Sciences and the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
Smart-Halajko MC, Robciuc MR, Cooper JA, Jauhiainen M, Kumari M, Kivimaki M, Khaw KT, et al. Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2277-82. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
Foster CT, Dovey OM, Lezina L, Luo JL, Gant TW, Barlev N, Bradley A, Cowley SM. Mol Cell Biol. 2010 Aug 16. [Epub ahead of print]. (With the department of Biochemistry, Âé¶¹ÊÓÆµ)
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Dovey OM, Foster CT, Cowley SM. Proc Natl Acad Sci U S A. 2010 May 4; 107(18):8242-7. (With the department of Biochemistry, Âé¶¹ÊÓÆµ)
Genetic Architecture of Ambulatory Blood Pressure in the General Population: Insights From Cardiovascular Gene-Centric Array
Tomaszewski M, Debiec R, Braund PS, Nelson CP, Hardwick R, Christofidou P et al. Hypertension. 2010 Dec;56(6):1069-1076. Epub 2010 Nov 8. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)
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Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, Sarwar N, Sandhu MS, Ricketts SL, Butterworth AS, Di Angelantonio E, Boekholdt SM et al. Lancet. 2010 May 8;375(9726):1634-9. (With the department of Cardiovascular Sciences, Âé¶¹ÊÓÆµ)